Moves to hold a strike ballot at the Independent are expected to be confirmed today at an NUJ chapel meeting, the union says.
It follows the breakdown of talks to prevent the compulsory redundancy of education features editor Lucy Hodges.
Head of NUJ Publishing Barry Fitzpatrick said: "This is one redundancy too far following on from the those that led up to the Lebedev take over. It is not only a bad decision commercially but destroys the credibility of the new owner's promises to invest in quality journalism. If the Independent abandons its prime position on education it does not bode well for its future."